Endemic Fluorosis and Occurrence Gastrointestinal Disorders in Prakasam District A.P.

Endemic Fluorosis and Occurrence Gastrointestinal Disorders in Prakasam District A.P.



B. Tirumala Rao, Dr B. Venkateswarlu, Dr.C.V.Narasimha Murthy



Fluoride has been known to cause significant effect on
human health through drinking water. Excessive ingestion of fluorides
not only causes dental and skeletal fluorosis but also leads to gastro
intestinal disturbances. Prakasam district of Andhra Pradesh, India is
having severe fluorosis. In the present study epidemiological survey was
conducted in five villages of Prakasam district regarding the
incidence of Gastrointestinal symptoms such as loss of appetite,
indigestion, nausea, vomiting, bloody vomiting, Pain in the upper part
of the abdomen and blotting in the upper abdomen after eating. The
results showed that nausea was found in 23 % of population. Loss of
appetite was found in 18 % of villagers. Indigestion, bloody vomit was
very low (6%) Experimental results show that male albino rats with
ingestion of 4mg/L of fluorides for 120 days caused damage to the
intestinal mucosa and sub mucosa. The possible reasons for the
gastrointestinal problems and mechanism of action of fluorides on
gastrointestinal tract was discussed. 



10.22161/ijeab/2.2.35



http://ijeab.com/upload_document/issue_files/35%20IJEAB-MAR-2017-42-Endemic%20Fluorosis%20and%20Occurrence%20Gastrointestinal%20Disorders.pdf



http://ijeab.com/submit-paper/

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